| 25.09.2021 11:00 | FC Energie Cottbus | - | Hallescher FC | 1 | : | 2 |
| 25.09.2021 11:00 | VfL Wolfsburg | - | Chemnitzer FC | 2 | : | 0 |
| 25.09.2021 13:00 | RasenBallsport Leipzig | - | Hannover 96 | 1 | : | 3 |
| 25.09.2021 13:00 | FC Erzgebirge Aue | - | SG Dynamo Dresden | 0 | : | 2 |
| 25.09.2021 13:00 | Eintracht Braunschweig | - | F.C. Hansa Rostock | 0 | : | 0 |
| 25.09.2021 13:00 | Hertha BSC | - | FC Carl Zeiss Jena | 2 | : | 0 |
| 25.09.2021 15:00 | FC St. Pauli | - | 1. FC Union Berlin | 0 | : | 2 |
| 25.09.2021 15:00 | KSV Holstein Kiel | - | Hamburger SV | 2 | : | 1 |
| 26.09.2021 11:00 | SV Werder Bremen | - | Hertha 03 Zehlendorf | 2 | : | 1 |
Spielfrei: FC Viktoria 1889 Berlin
| Sp. | Pkt. | Tore | Diff. | |||
|---|---|---|---|---|---|---|
| 1 | Hertha BSC | 7 | 21 | 23:2 | 21 | |
| 2 | Hannover 96 | 6 | 16 | 10:4 | 6 | |
| 3 | VfL Wolfsburg | 7 | 15 | 16:8 | 8 | |
| 4 | Chemnitzer FC | 7 | 15 | 8:8 | 0 | |
| 5 | FC St. Pauli | 7 | 13 | 18:5 | 13 | |
| 6 | SG Dynamo Dresden | 6 | 12 | 12:5 | 7 | |
| 7 | 1. FC Union Berlin | 7 | 12 | 11:5 | 6 | |
| 8 | RasenBallsport Leipzig | 7 | 12 | 9:9 | 0 | |
| 9 | Hamburger SV | 6 | 10 | 13:8 | 5 | |
| 10 | FC Viktoria 1889 Berlin | 6 | 9 | 9:9 | 0 | |
| 11 | SV Werder Bremen | 6 | 9 | 12:13 | -1 | |
| 12 | F.C. Hansa Rostock | 7 | 8 | 9:13 | -4 | |
| 13 | FC Erzgebirge Aue | 7 | 7 | 5:9 | -4 | |
| 14 | KSV Holstein Kiel | 6 | 6 | 8:15 | -7 | |
| 15 | Eintracht Braunschweig | 6 | 4 | 6:12 | -6 | |
| 16 | FC Carl Zeiss Jena | 7 | 4 | 3:13 | -10 | |
| 17 | Hallescher FC | 7 | 4 | 6:25 | -19 | |
| 18 | Hertha 03 Zehlendorf | 7 | 3 | 8:13 | -5 | |
| 19 | FC Energie Cottbus | 7 | 3 | 7:17 | -10 |
Hinweis: Tabellenstand ohne vorgezogene Spiele!
Spielfrei: FC Viktoria 1889 Berlin