| 20.11.2021 11:00 | Hallescher FC | - | KSV Holstein Kiel | 1 | : | 0 |
| 20.11.2021 11:00 | Hannover 96 | - | F.C. Hansa Rostock | 1 | : | 1 |
| 20.11.2021 13:00 | FC Viktoria 1889 Berlin | - | RasenBallsport Leipzig | 0 | : | 0 |
| 20.11.2021 13:00 | VfL Wolfsburg | - | VfL Osnabrück | 2 | : | 3 |
| 20.11.2021 14:00 | Hertha BSC | - | FC St. Pauli | 4 | : | 2 |
| 01.12.2021 18:30 | SG Dynamo Dresden | - | Chemnitzer FC | 2 | : | 0 |
| 08.02.2022 13:00 | SV Werder Bremen | - | FC Carl Zeiss Jena | 3 | : | 2 |
| 23.02.2022 15:00 | 1. FC Union Berlin | - | FC Energie Cottbus | 0 | : | 0 |
| 12.03.2022 14:00 | 1. FC Magdeburg | - | Hamburger SV | 6 | : | 2 |
Spielfrei: Eimsbütteler TV
| Sp. | Pkt. | Tore | Diff. | |||
|---|---|---|---|---|---|---|
| 1 | Hertha BSC | 9 | 25 | 25:11 | 14 | |
| 2 | SV Werder Bremen | 9 | 21 | 27:17 | 10 | |
| 3 | FC Energie Cottbus | 10 | 20 | 14:11 | 3 | |
| 4 | KSV Holstein Kiel | 9 | 19 | 17:11 | 6 | |
| 5 | RasenBallsport Leipzig | 9 | 15 | 18:11 | 7 | |
| 6 | SG Dynamo Dresden | 10 | 15 | 15:10 | 5 | |
| 7 | Hannover 96 | 9 | 15 | 12:9 | 3 | |
| 8 | 1. FC Union Berlin | 9 | 13 | 13:11 | 2 | |
| 9 | VfL Wolfsburg | 10 | 13 | 16:15 | 1 | |
| 10 | Hallescher FC | 10 | 13 | 11:18 | -7 | |
| 11 | FC Viktoria 1889 Berlin | 10 | 12 | 13:12 | 1 | |
| 12 | VfL Osnabrück | 9 | 11 | 10:15 | -5 | |
| 13 | Hamburger SV | 10 | 10 | 15:21 | -6 | |
| 14 | F.C. Hansa Rostock | 10 | 9 | 17:16 | 1 | |
| 15 | Chemnitzer FC | 9 | 9 | 9:14 | -5 | |
| 16 | FC St. Pauli | 10 | 9 | 16:22 | -6 | |
| 17 | Eimsbütteler TV | 9 | 8 | 11:19 | -8 | |
| 18 | 1. FC Magdeburg | 9 | 6 | 14:21 | -7 | |
| 19 | FC Carl Zeiss Jena | 10 | 5 | 10:19 | -9 |
Hinweis: Tabellenstand ohne vorgezogene Spiele!
| 27.11.2021 11:00 | Eimsbütteler TV | - | SG Dynamo Dresden | 0 | : | 2 |
| 27.11.2021 14:00 | Hamburger SV | - | 1. FC Union Berlin | 5 | : | 1 |
| 27.11.2021 14:00 | FC Carl Zeiss Jena | - | Hertha BSC | 0 | : | 2 |
| 28.11.2021 15:00 | VfL Osnabrück | - | SV Werder Bremen | 2 | : | 3 |
| 12.02.2022 11:00 | FC St. Pauli | - | 1. FC Magdeburg | 2 | : | 1 |
| 12.02.2022 11:00 | KSV Holstein Kiel | - | VfL Wolfsburg | 1 | : | 1 |
| 12.02.2022 13:00 | RasenBallsport Leipzig | - | Hallescher FC | 7 | : | 0 |
| 12.03.2022 11:00 | FC Energie Cottbus | - | Hannover 96 | 4 | : | 3 |
| 27.03.2022 12:00 | Chemnitzer FC | - | FC Viktoria 1889 Berlin | 0 | : | 3 |
Spielfrei: F.C. Hansa Rostock